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KMID : 0870420110150030171
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Korean Journal of Hepato-Biliary-Pancreatic Surgery
2011 Volume.15 No. 3 p.171 ~ p.178
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Adenocarcinoma of the ampulla of Vater: predictors of survival and recurrence after curative radical resection
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Kim Kang-Jae
Choi Dong-Wook
Kim Woo-Seok
Kim Min-Jung
Song Sun-Choon
Heo Jin-Seok
Choi Seong-Ho
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Abstract
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Backgrounds/Aims : Because of low incidence rates, there have been few reports on the patterns of and risk factors for recurrence after curative resection of the ampulla of Vater (AoV) cancer. The aim of this study was to characterize patterns of recurrence and to evaluate risk factors affecting survival rates and recurrence after curative resection.
Methods: Medical records of 181 patients who had undergone pancreaticoduodenectomy with curative intent for AoV adenocarcinoma between December 1994 and March 2010 at Samsung Medical Center were retrospectively reviewed. Factors influencing on overall survival rate, recurrence rates, and recurrence patterns were analyzed.
Results:
Conclusions: AoV adenocarcinoma has a better prognosis than other periampullary carcinomas, but still has a high recurrence rate, especially during the first three years after curative radical resection. Therefore, careful follow-up is needed during the first 3 years, especially for the higher risk group. Further study of adjuvant therapy to decrease recurrence after curative resection is now warranted.
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KEYWORD
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Ampulla of Vater, Adenocarcinoma, Pancreaticoduodenectomy, Prognosis, Recurrence
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